Table 2 The outcomes of peri-operative prophylaxis with cefazolin/cefuroxime or other antibiotics during VATLS
Outcomes | Before PSM | After PSM | ||||||
|---|---|---|---|---|---|---|---|---|
With cefazolin/cefuroxime (n = 152) | With Other antibiotics (n = 420) | Relative Risk (95% CI) | p | With cefazolin/cefuroxime (n = 141) | With Other antibiotics (n = 141) | Relative Risk (95% CI) | p | |
Primary outcome | ||||||||
Pulmonary infection | 36 (23.7) | 128 (30.5) | 0.777 (0.564 ~ 1.070) | 0.113 | 36 (25.5) | 43 (30.5) | 0.837 (0.575 ~ 1.220) | 0.353 |
Secondary outcomes | ||||||||
Post-operative fever | 16 (10.5) | 32 (7.6) | 1.382 (0.781 ~ 2.445) | 0.268 | 16 (11.3) | 13 (9.2) | 1.231 (0.615 ~ 2.463) | 0.556 |
WBC count on the 3rd day after surgery, × 109/L | 9.07 ± 2.12 | 8.34 ± 2.39 | 0.100 | 9.14 ± 2.15 | 8.75 ± 2.74 | 0.190 | ||
Neutrophils on the 3rd day after surgery, % | 73.49 ± 6.97 | 72.40 ± 8.54 | 0.481 | 73.36 ± 7.09 | 73.09 ± 8.46 | 0.769 | ||
Time for post-operative blood-RT recoverya | 3 (3,6) | 4 (4, 6) | 0.707 | 4 (3, 6) | 4 (4, 6) | 0.574 | ||