Table 1 Baseline characteristics of patients enrolled before and after propensity score matching
Variable | Before PSM | After PSM | ||||
|---|---|---|---|---|---|---|
With cefazolin/cefuroxime (n = 152) | With Other antibiotics (n = 420) | p | With cefazolin/cefuroxime (n = 141) | With Other antibiotics (n = 141) | p | |
Sex | ||||||
Female | 0 (0.0) | 8 (1.9) | 0.190 | 0 (0.0) | 5 (3.5) | 0.071 |
Male | 152 (100.0) | 412 (98.1) | 141 (100.0) | 136 (96.5) | ||
Age, years (IQR) | 61 (58, 66) | 62 (55, 67) | 0.995 | 61 (58, 66) | 62 (57, 67) | 0.521 |
BMI, kg/m2 (Mean) | 23.78 ± 2.72 | 23.31 ± 2.95 | 0.088 | 23.68 ± 2.64 | 23.51 ± 3.14 | 0.638 |
Comorbidities | ||||||
Respiratory system | ||||||
Yes | 19 (12.5) | 82 (19.5) | 0.048 | 19 (13.5) | 16 (11.3) | 0.588 |
No | 133 (87.5) | 338 (80.5) | 122 (86.5) | 125 (88.7) | ||
Circulatory system | ||||||
Yes | 105 (69.1) | 253 (60.2) | 0.050 | 94 (66.7) | 97 (68.8) | 0.702 |
No | 47 (30.9) | 167 (39.8) | 47 (33.3) | 44 (31.2) | ||
Digestive system | ||||||
Yes | 19 (12.5) | 35 (83.) | 0.132 | 19 (13.5) | 10 (7.1) | 0.108 |
No | 133 (87.5) | 385 (91.7) | 122 (86.5) | 131 (92.9) | ||
Urinary system | ||||||
Yes | 16 (10.5) | 30 (7.1) | 0.189 | 16 (11.3) | 11 (7.8) | 0.312 |
No | 136 (89.5) | 390 (92.9) | 125 (88.7) | 130 (92.2) | ||
Endocrine system | ||||||
Yes | 31 (20.4) | 71 (16.9) | 0.335 | 25 (17.7) | 21 (14.9) | 0.519 |
No | 121 (79.6) | 349 (83.1) | 116 (82.3) | 120 (85.1) | ||
Contagious disease | ||||||
Yes | 4 (2.6) | 7 (1.7) | 0.691 | 4 (2.8) | 3 (2.1) | 1.000 |
No | 148 (97.4) | 413 (98.3) | 137 (97.2) | 138 (97.9) | ||
Number of cigarettes smoked, days (IQR) | 20 (20, 20) | 20 (10, 20) | 0.126 | 20 (20, 20) | 20 (10, 20) | 0.068 |
Smoking time, years (IQR) | 30 (20, 35) | 30 (20, 40) | 0.267 | 30 (20, 35) | 30 (20, 40) | 0.834 |
Quit smoking, years | ||||||
<1 year | 104 (68.4) | 320 (76.2) | 0.061 | 99 (70.2) | 103 (73.0) | 0.597 |
≥1 years | 48 (31.6) | 100 (23.8) | 42 (29.8) | 38 (27.0) | ||
Pre-operative stay, days (IQR) | 7.5 (5.0, 9.0) | 7.0 (6.0, 10.0) | 0.366 | 8 (5.5, 9.5) | 7 (6, 9) | 0.947 |
Pre-operative antibiotics use | ||||||
Yes | 72 (47.4) | 264 (62.9) | 0.001 | 72 (51.1) | 77 (54.6) | 0.551 |
No | 80 (52.6) | 156 (37.1) | 69 (49.9) | 64 (45.4) | ||
FEV1/FVC, % | ||||||
≥70% | 108 (71.1) | 240 (57.1) | 0.003 | 97 (68.8) | 96 (68.1) | 0.898 |
<70% | 44 (28.9) | 180 (42.9) | 44 (31.2) | 45 (31.9) | ||
COPD history | ||||||
Yes | 6 (3.9) | 38 (9.0) | 0.043 | 6 (4.3) | 6 (4.3) | 1.000 |
No | 146 (96.1) | 382 (91.0) | 135 (95.7) | 135 (95.7) | ||
Baseline WBC count, × 109/L (IQR) | 6.00 (4.88, 6.80) | 6.13 (4.83, 6.86) | 0.680 | 6.02 (4.88, 6.80) | 6.13 (4.83, 7.11) | 0.899 |
Baseline neutrophils, % (IQR) | 55.7 (52.0, 64.6) | 58.1 (52.7, 62.5) | 0.571 | 55.7 (51.8, 64.6) | 58.1 (51.3, 63.2) | 0.707 |
Baseline blood glucose, mmol/L (IQR) | 4.88 (4.63, 5.44) | 5.00 (4.68, 5.53) | 0.165 | 4.87 (4.63, 5.41) | 5.00 (4.60, 5.63) | 0.172 |
Type of resection | ||||||
Wedge resection | 27 (17.8) | 49 (11.7) | 0.137 | 25 (17.7) | 22 (15.6) | 0.558 |
Segmental resection | 62 (40.8) | 172 (41.0) | 58 (41.1) | 52 (36.9) | ||
Lobectomy | 63 (41.4) | 199 (47.4) | 58 (41.1) | 67 (47.5) | ||
Surgical site | ||||||
Left lung | 69 (45.4) | 173 (41.2) | 0.369 | 63 (44.7) | 63 (44.7) | 1.000 |
Right lung | 83 (54.6) | 247 (58.8) | 78 (55.3) | 78 (55.3) | ||
Duration of VATLS, hours (IQR) | 2.3 (1.9, 2.9) | 2.4 (1.8, 3.0) | 0.536 | 2.42 (1.95, 2.95) | 2.43 (1.97, 3.26) | 0.248 |