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Table 3 Univariate and multivariate logistic regression analysis of characteristics associated with lateral lymph node metastasis

From: Distinct risk factors of lateral lymph node metastasis in patients with papillary thyroid cancer based on age stratification

 

Univariate analysis

  

Multivariate analysis

 

Characteristic

OR

95% CI

p value

 

OR

95% CI

p value

Age(years)

  

0.015

   

0.020

> 45

0.488

0.267–0.891

0.019

 

0.030

0.206–0.921

0.030

30–45

0.933

0.520–1.674

0.817

 

0.999

0.511–1.952

0.998

≤ 30

1.000

   

1.000

  

Gender

  

0.006

   

0.030

Male

2.089

1.239–3.520

  

1.916

1.064–3.452

 

Female

1.000

   

1.000

  

Tumor size

  

0.010

   

0.002

≥ 20 mm

2.328

1.221–4.437

  

3.212

1.535–6.822

 

< 20 mm

1.000

   

1.000

  

Location

  

0.013

   

< 0.001

Upper lobe

1.992

1.159–3.423

  

3.874

1.997–7.517

 

Others

1.000

   

1.000

  

Multifocality

 

< 0.001

   

0.006

Present

2.728

1.751–4.251

  

3.108

1.378–7.009

 

Absent

1.000

   

1.000

  

Bilaterality

  

0.002

   

0.991

Present

2.029

1.287-3.200

  

1.005

0.429–2.353

 

Absent

1.000

   

1.000

  

Extra-thyroidal extension

< 0.001

   

0.022

Present

2.566

1.592–4.137

  

1.962

1.104–3.487

 

Absent

1.000

   

1.000

  

Extra-nodal extension

< 0.001

   

0.024

Present

4.333

2.295–8.184

  

2.227

1.111–4.464

 

Absent

1.000

   

1.000

  

CLNM

  

< 0.001

   

< 0.001

Present

5.611

3.480–9.045

  

5.299

2.948–9.527

 

Absent

1.000

   

1.000