Table 5 Pathological data of the study patients

Size (cm)

6 (1.5–20)

4 (1.5–4.5)

6 (5–9.5)

11 (10–20)

0.001

Number

0.016

 Single

272 (86.3%)

82 (93.2%)

144 (86.2%)

46 (76.7%)

 Multiple

43 (13.7%)

6 (6.8%)

23 (13.8%)

14 (23.3%)

Resection margin

0.021

 R0

275 (87.3%)

80 (90.9%)

149 (89.2%)

46 (76.7%)

 R1

40 (12.7%)

8 (9.1%)

18 (10.8%)

14 (23.3%)

Capsular invasion

116 (36.8%)

36 (40.9%)

62 (37.1%)

18 (30%)

0.399

Microvascular invasion

147 (46.7%)

31 (35.2%)

74 (44.3%)

42 (70%)

0.001

Perineural invasion

122 (38.7%)

27 (30.7%)

61 (36.5%)

34 (56.7%)

0.004

Tumor Grade

0.002

 I

57 (18.1%)

18 (20.5%)

33 (19.8%)

6 (10%)

 II

187 (59.4%)

55 (62.5%)

104 (62.3%)

28 (46.7%)

 III

61 (19.4%)

12 (13.6%)

28 (16.8%)

21 (35%)

 IV

9 (2.9%)

2 (2.3%)

2 (1.2%)

5 (8.3%)

 No viable tumor

1 (0.3%)

1 (1.1%)

0

0

Liver background

0.04

 Cirrhosis

298 (94.6%)

86 (97.7%)

159 (95.2%)

53 (88.3%)

 Normal

17 (5.4%)

2 (2.3%)

8 (4.8%)

7 (11.7%)