From: Different doses of nalmefene combined with hydromorphone hydrochloride for postoperative analgesia after colorectal surgery: a randomized controlled study
Group N1
(2 µg/kg)
(n = 31)
Group N2
(0.5 µg/kg)
Group C
χ2 value
Fisher exact test
P value
Nausea %
7(4.5)
13(8.4)
12(7.7)
2.081
0.353
Vomiting %
3(1.9)
1(0.6)
2(1.3)
1.044
0.875
Pruritus %
0(0)
4(2.6)
5.706
0.036