Table 1 General characteristics of included studies
Author | Country | Design | Type of surgery | Ethnicity | Patients | Time of blood collection | anastomotic leak | NOS score | |||
|---|---|---|---|---|---|---|---|---|---|---|---|
Yes | No | ||||||||||
N | NLR | N | NLR | ||||||||
Cikot, M 2018 [16] | Turkey | P | Gastric | White people | Patients undergoing elective anastomosis because of benign or malignant underlying gastrointestinal etiologies | 12 hours before surgery | 27 | 1.93 ± 0.88 | 73 | 1.85 ± 1.00 | 7 |
Palioginnis, P 2020 [19] | Italy | R | Colorectal | White people | Patients with colorectal cancer undergoing elective surgical procedure with an open or laparoscopic approach | Pre-operatively | 106 | 3.23 ± 1.39 | 1326 | 2.96 ± 1.33 | 8 |
Radulescu, D 2020 [4] | Romania | R | Gastric | White people | Patients with gastric cancer undergoing surgery | At the moment of admission to hospital | 16 | 5.83 ± 1.68 | 188 | 2.44 ± 0.51 | 6 |
Radulescu, D 2020 [20] | Romania | R | Colorectal | White people | Patients undergoing surgery for colon and rectal cancer | Pre-operatively before any hydroelectrolytic or protein balancing treatment | 27 | 5.10 ± 2.02 | 134 | 2.27 ± 0.60 | 7 |
Romano, L 2020 [22] | Italy | P | Gastric | White people | Patients who underwent laparoscopic sleeve gastrectomy | The day before the operation | 6 | 1.74 ± 0.09 | 145 | 1.84 ± 0.20 | 7 |
Sato, Sh 2020 [23] | Japan | R | Esophageal | East Asian | Patients with esophageal cancer undergoing esophagectomy with retrosternal reconstruction of the gastric conduit | Pre-operatively | 38 | 3.23 ± 4.16 | 210 | 5.38 ± 9.06 | 8 |
Suzuki, N 2020 [24] | Japan | R | Colorectal | East Asian | Patients with rectal cancer undergoing low anterior resection | Pre-operatively | 21 | 2.90 ± 0.79 | 115 | 2.46 ± 1.12 | 7 |
Yuliandar, AA 2020 [11] | Indonesia | R | Colorectal | East Asian | Colorectal cancer patients undergoing elective surgery | 1 day before surgery | 14 | 8.60 ± 7.86 | 40 | 5.17 ± 8.56 | 6 |
Huang, JX 2021 [17] | China | R | Esophageal | East Asian | Children with congenital esophageal atresia who underwent one-stage anastomosis in our hospital | Pre-operatively | 28 | 3.13 ± 1.89 | 79 | 3.30 ± 1.88 | 7 |
Li, Sh. 2021 [18] | China | R | Esophageal | East Asian | Patients with esophageal cancer undergoing video-assisted esophageal resection | Pre-operatively | 27 | 6.05 ± 9.95 | 64 | 2.98 ± 2.26 | 7 |
Rodriguez, Q 2021 [21] | Mexico | R | Gastric | White people | Patients with gastric cancer undergoing total gastrectomy | At admission 1 day previous to the operation | 18 | 6.75 ± 5.65 | 40 | 5.05 ± 3.23 | 6 |
Wu, CX 2021 [25] | China | R | Esophageal | East Asian | Patients with esophageal cancer undergoing radical esophagectomy | Pre-operatively | 25 | 4.44 ± 4.74 | 173 | 4.15 ± 6.60 | 6 |