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Table 3 Comparison of perioperative effects between the two stages

From: The learning curve for laparoscopic pancreaticoduodenectomy by a proficient laparoscopic surgeon: a retrospective study at a single center

Clinical factor

Mode of operation

P value

Learning improvement stage (n = 35)

Proficiency stage (n = 75)

Days from surgery to discharge (days)

19.4 ± 2.6

14.9 ± 3.2

 < 0.05

Operation time (minutes)

376.9 ± 48.2

294.4 ± 18.7

 < 0.05

Intraoperative blood loss (ml)

375.1 ± 194.3

241 ± 123.8

 < 0.05

Pancreatic fistula

  

0.049

 No pancreatic fistula or biochemical leakage

25 (71.4%)

76 (89.4%)

 

 Grade B pancreatic fistula

7 (20.0%)

6 (7.1%)

 

 Grade C pancreatic fistula

3 (8.6%)

3 (3.5%)

 

Biliary fistula

  

0.094

 no

29 (82.9%)

79 (92.9%)

 

 yes

6 (17.1%)

6 (7.1%)

 

Gastrointestinal fistula

  

0.972

 no

33 (94.3%)

80 (94.1%)

 

 yes

2 (5.7%)

5 (5.9%)

 

gastroplegia

  

0.351

 no

33 (94.3%)

83 (97.6%)

 

 yes

2 (5.7%)

2 (2.4%)

 

Anal exhaust time (days)

3.1 ± 0.9

2.7 ± 0.8

0.027

Postoperative feeding time (days)

3.3 ± 0.8

2.7 ± 0.8

0.001

Postoperative bleeding

  

0.070

 no

30 (85.7%)

81 (95.3%)

 

 yes

5 (14.3%)

4 (4.7%)

 

abdominal infection

  

0.008

 no

28 (80.0%)

81 (95.3%)

 

 yes

7 (20.0%)

4 (4.7%)

 

Reoperation

  

0.412

 no

30 (85.7%)

80 (94.1%)

 

 yes

5 (14.3%)

5 (5.9%)

 

Perioperative death

  

0.852

 no

33 (97.1%)

85 (98.8%)

 

 yes

1 (2.9%)

1 (1.2%)