Applying the en-bloc technique in corpus callosum glioblastoma surgery contributes to maximal resection and better prognosis: a retrospective study

Table 4 Multivariate Cox regression analysis of overall survival and progression free survival

Factors	Overall survival			Progression free survival
Factors	P	HR	95% CI	P	HR	95% CI
Location
Anterior (Rostrum+Genu)	< 0.001	0.370	0.221–0.618	0.032	/	/
Posterior (Isthmus+Spleniu)	0.008	0.447	0.247–0.810	0.195	/	/
Body	Reference			Reference
Pathology
Astrocytoma, WHO 4, IDH mutation	0.004	0.483	0.295–0.791	0.033	0.613	0.390–0.962
Glioblastoma	Reference			Reference
En-bloc technique
Yes	< 0.001	0.316	0.189–0.530	0.040	0.624	0.398–0.978
No	Reference			Reference
EOR
SMR	< 0.001	0.310	0.192–0.500	< 0.001	0.376	0.238–0.593
TR	Reference			Reference

HR Hazard ratio, CI Confidence interval, EOR Extent of resection, SMR Supramaximal resection, TR Total resection, KPS Karnofsky Performance Status scores.

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