Evaluation of the correlation of vasculogenic mimicry, ALDH1, KAI1 and microvessel density in the prediction of metastasis and prognosis in colorectal carcinoma

Table 3 Results of univariate analyses of overall survival (OS) time

Variable	n	Mean OS (months)	Log-rank	P value
ALDH1			16.908	<0.001
Negative	54	64.3 ± 21.9
Positive	150	47.1 ± 22.4
VM			86.416	<0.001
Negative	129	61.5 ± 20.0
Positive	75	34.7 ± 19.0
MVD			15.610	<0.001
< 21 group	95	59.4 ± 21.9
≥ 21 group	109	44.9 ± 22.8
KAI1			60.613	<0.001
Negative	139	42.9 ± 21.2
Positive	65	70.4 ± 16.1
Gender			0.174	0.677
Male	120	53.5 ± 21.9
Female	84	49.0 ± 25.5
Ages (year)			0.063	0.802
< 60	81	51.9 ± 23.3
≥ 60	123	51.5 ± 23.7
Size (cm)			0.392	0.531
< 5.0 ≥ 5.0	119 85	51.0 ± 23.3 52.5 ± 23.8
Location			2.610	0.106
Rectum	105	49.7 ± 24.5
Colon	99	53.7 ± 22.3
Grade			1.266	0.531
Well	45	55.4 ± 24.7
Moderate	107	51.4 ± 22.9
Poor	52	48.9 ± 23.5
Invasion			9.604	0.002
Subserosa	113	56.9 ± 22.6
Visceral peritoneum	91	45.1 ± 22.9
Distant metastasis			3.717	0.054
No	176	53.4 ± 23.2
Yes	28	40.8 ± 22.7
LNM			19.908	<0.001
No	122	59.4 ± 19.7
Yes	82	40.0 ± 23.9
TNM stage			53.120	<0.001
Iand II	125	60.3 ± 19.9
III and IV	79	37.9 ± 22.2

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