Chest closure without drainage after open patent ductus arteriosus ligation in Ugandan children: A non blinded randomized controlled trial

Table 1 Fixed nominal rule to maintain overall type I error = 0.05

	Total number of analyses planned (including final)
Analysis	1	2	3	4	5
1^st	α = 0.05	0.029	0.022	0.018	0.016
2^nd		0.029	0.022	0.018	0.016
3^rd			0.022	0.018	0.016
4^th				0.018	0.016
5^th					0.016

Ref: Pocock SJ. Clinical Trials: A Practical Approach. Chichester: Wiley; 1984
The bolded numbers show the levels of significance that will be used at the corresponding analysis

ISSN: 1471-2482