Inclusion criteria | Exclusion criteria |
---|---|
patients meeting all of the following criteria are considered for inclusion in the study: | patients with any of the following will not be included in the trial: |
- scheduled for elective major partial liver resection of ≥3 liver segments for liver neoplasms | - patients <18 and >90 years |
- written informed consent | - patients <50 and >120 kg |
- adequate contraception is required for women with childbearing potential | - patients with severe, organ-specific disorders (e.g., liver or renal failure, acute pancreatitis) |
- patients undergoing emergency procedures | |
- patients with expected intubation problems | |
- pregnancy and/or lactation | |
- history of hypersensitivity to the investigational product or to any drug with similar chemical structure or to any compound present in the pharmaceutical form of the investigational product | |
- simultaneous participation in another clinical trial | |
- mental condition rendering the subject incapable of understanding the nature, scope, and consequences of the trial | |
No subject will be enrolled in this study more than once. |