From: Diagnostic value of blood inflammatory markers for detection of acute appendicitis in children
Criterion | Sensitivity | 95% CI | Specificity | 95% CI | AUC | sign. | 95% CI | ||
---|---|---|---|---|---|---|---|---|---|
1 vs. 4 | WBC | >14.3 | 80 | 51.9 – 95.4 | 62.5 | 24.7 – 91.0 | 0.667 | n.s. | 0.442 – 0.847 |
IL-6 | >12.2 | 93.3 | 68.0 – 98.9 | 100 | 62.9 – 100.0 | 0.992 | <.005 | 0.836 – 1.000 | |
CRP | >11 | 86.7 | 59.5 – 98.0 | 100 | 62.9 – 100.0 | 0.937 | <.01 | 0.752 – 0.992 | |
1 vs. 3+4 | WBC | >14.3 | 75.8 | 57.7 – 88.9 | 62.5 | 24.7 – 91.0 | 0.644 | n.s. | 0.479 – 0.787 |
IL-6 | >12.2 | 75.8 | 57.7 – 88.9 | 100 | 62.9 – 100.0 | 0.903 | <.01 | 0.770 – 0.973 | |
CRP | >11 | 69.7 | 51.3 – 84.4 | 100 | 62.9 – 100.0 | 0.843 | <.05 | 0.695 – 0.937 | |
2 vs. 4 | WBC | >18 | 73.3 | 44.9 – 92.0 | 58.8 | 33.0 – 81.5 | 0.569 | n.s. | 0.382 – 0.741 |
IL-6 | >21.7 | 86.7 | 59.5 – 98.0 | 82.4 | 56.6 – 96.0 | 0.833 | <.02 | 0.660 – 0.940 | |
CRP | >42 | 80 | 51.9 – 95.4 | 94.1 | 71.2 – 99.0 | 0.894 | <.005 | 0.734 – 0.974 | |
2 vs. 3+4 | WBC | >12.6 | 87.9 | 71.8 – 96.5 | 41.2 | 18.5 – 67.0 | 0.542 | n.s. | 0.395 – 0.684 |
IL-6 | >21.7 | 63.6 | 45.1 – 80.1 | 82.4 | 56.6 – 96.0 | 0.736 | <.05 | 0.592 – 0.851 | |
CRP | >26 | 66.7 | 48.1 – 83.1 | 82.4 | 56.6 – 96.0 | 0.731 | n.s. | 0.587 – 0.846 | |
3 vs. 4 | WBC | >18.2 | 73.3 | 44.9 – 92.0 | 61.1 | 35.3 – 82.9 | 0.613 | n.s. | 0.428 – 0.777 |
IL-6 | >23.1 | 86.7 | 59.5 – 98.0 | 66.7 | 41.0 – 86.6 | 0.719 | n.s. | 0.535 – 0.860 | |
CRP | >46 | 80 | 51.9 – 95.4 | 88.9 | 65.2 – 98.3 | 0.835 | <.05 | 0.665 – 0.940 | |
1+2 vs. 3+4 | WBC | >12.6 | 87.9 | 71.8 – 96.5 | 44 | 24.4 – 65.1 | 0.575 | n.s. | 0.438 – 0.703 |
IL-6 | >12.2 | 75.8 | 57.7 – 88.9 | 76 | 54.9 – 90.6 | 0.79 | n.s. | 0.663 – 0.886 | |
CRP | >26 | 60.6 | 42.1 – 77.1 | 88 | 68.8 – 97.3 | 0.767 | n.s. | 0.637 – 0.868 |