The target population was all non-institutionalised female subjects suffering from a chronic disease for at least 6 months.
The patients were recruited in the period from January-December 2011.
Exclusion criteria were as follows: male sex, presence of organic diseases and in particular of oncologic diseases, previous diagnosis of psychopathological disorders (personality disorders, mood disorders, schizophrenia and other psychotic disorders, use disorder psychoactive substances), current psychopharmacological treatment.
The methodological approach was based on administration of the following test: the Short Form health survey SF-36 , the Symptom Check List SCL-90-R , the Satisfaction Profile questionnaire (SAT-P)  and the Beck Depression Inventory-II (BDI-II) .
The Short Form SF-36 health survey  has been chosen because widely used to evaluate the QoL. It is a 36 item survey measuring health-related QoL. The following 8 subscales are constructed from the 36 items: Vitality (V), physical functioning (PF), bodily pain (BP), general health perceptions (GHP), physical role functioning (PRF), emotion role functioning (ERF), social role functioning (SRF), mental health (MH). Two summary measures known as the Physical Health Component Score (PCS) and the Mental Health Component Score (MCS) are derived. All the scales and summary measure are positively scored.
The Symptom Check List SCL-90-R, was used to obtain a subjective measurement of the state of the patient referring to the presence of symptoms in the last week. The SCL-90-R is a widely-used questionnaire that consists of 90 items, for self-report of psychological distress and multiple aspects of psychopathology, as part of the evaluation of chronic pain patients and other non-psychiatric populations . From the 90 items the following subscales are derived: Somatization, Obsessive-Compulsive, Interpersonal Sensitivity, Depression, Anxiety, Hostility, Phobic Anxiety, Paranoid Ideation, Psychoticism, Sleep Disorders. The global severity index (GSI) was designed to measure overall psychological distress.
The Satisfaction Profile questionnaire (SAT-P) allowed investigating the subjective satisfaction of some aspects of daily life. The questionnaire is based on 32 items; for each item the subject is asked to provide an assessment of his level of subjective satisfaction, referring to last month. From the 32 items the following subscales are derived: Psychological Functioning, Physical Functioning, Work, Sleep/Eating/Leisure, Social Functioning.
The Beck Depression Inventory–II (BDI–II), a self-report instrument frequently used in clinical and research settings to assess depression severity was used in the Italian adaptation form. It consists of 21 groups of statements to be evaluated on a four-point scale, referring to how the subject felt in the last two weeks. From the 21 groups of statements the following subscales are derived: Somatic-Affective component and Cognitive component.
The Pearson correlation coefficient was used to evaluate the relationship between subjective perception of their state of health (physical and psychological-emotional) and psychopathological states present in the patients. The scores obtained respectively on 8 scales of the SF-36 and on the 10 dimensions of SCL-90-R, and the scores obtained respectively on the 5 scales of the test SAT-P and 3 factors inventory BDI-II were compared.